Research Output
Most research projects of the Lab of General Biochemistry and Physical Pharmacy are in close collaboration with universities from various European countries, which is facilitated through significant funding by Flemisch Agencies and the European Union. Our groups participated/participate in:
- DELNAM (H2020)
- COMPACT (Imi)
- NICHE (EU-Euronanomed II)
- NANOMED (EU ETN-Marie Curie Action)
- European Research Council (ERC)/NANOBUBBLE/Prof. Braeckmans, RESPIRNA/Prof. Raemdonck.
- Kom op tegen Kanker
- NanoCardio (Interreg)
- FWO
- VLAIO
- Koning BoudewijnStichting
2019 – S.C. De Smedt, R. Verbeke, H. Dewitte, I. Lentacker
Priority date: 12/04/2019
Application number: EP19168853.0
2018 – K. Braeckmans, S.C. De Smedt, J. Fraire
Priority date: 18/12/2018
Application number: EP18213548.3
2018 – S.C. De Smedt, K. Braeckmans, F. Sauvage
Priority: 08/10/2018
Application number: EP18199111.8
Entering PCT (not yet published)
2017 – K. Raemdonck, F. Joris, S. Stremersch, S. De Smedt
Priority: 19/01/2017
Application number: EP17152264.2
Entering PCT (not yet published)
2016 – K. Raemdonck, S. De Smedt
Priority: 24/11/2016
Application number: EP16200515.1
Entering PCT (not yet published)
2015 – A. Skirtach, J. Demeester, S. De Smedt, S. Stremersch, K. Raemdonck, K. Braeckmans
Entering PCT (not yet published)
2015 – K. Braeckmans, R. Xiong, S.K. Samal, S. De Smedt
Entering PCT
2014 – K. Braeckmans, S. De Smedt, J.Demeester, T. Coenye
Entering PCT (not yet published)
2012 – K. Braeckmans, H. Deschout, J. Demeester, S.C. De Smedt
Priority: 09/07/2010
Assigned in designated countries:
US9483440 (B2), EP2591333 (A1) under examination
Owner: UGent
2011 – K. Braeckmans, H. Deschout, K. Neyts, J. Demeester, S.C. De Smedt
Priority
Assigned in designated countries:
US8928875 (B2), EP2513628 (A1) under examination
Owner: UGent
2010 – K. Braeckmans, H. Deschout, J. Demeester and S.C. De Smedt
Priority: 9/7/2010
Assigned in designated countries:
US9483440 (B2), EP2591333 still under examination
Owner: UGent
2010 – S.C. De Smedt, J. Demeester, C. Huang, B. Lucas
Priority: 18/12/2009
Assigned in designated countries:
WO2011073442 (A1) Withdrawn
2006 – S.C. De Smedt, J. Demeester, B. De Geest and S. Derveaux
Priority: 20/10/2006
Assigned in designated countries:
EP1903337 (B1) withdrawn, JP5752881 (B2), US2010081215 (A1) still under examination (after ‘final rejection’)
Owner: Mycartis NV
2005 – S.C. De Smedt, J. Demeester and B. De Geest
Priority: 14/6/2005
Assigned in designated countries:
EP1733718 (A1)
2001 – N. Sanders, S. De Smedt and J. Demeester
Priorty: 13/4/2001
Assigned in designated countries:
US7432308 (B2)
2001 – B. Stubbe, S.C. De Smedt and J. Demeester
Priority: 21/12/2001
Assigned in designated countries:
EP1455832 (B1)
2001 – K. Braeckmans, S.C. De Smedt, J. Demeester, C. Roelant and M. Leblans
Priority: 19/10/2000
Assigned in designated countries:
ZA200303008 (B), US8735172 (B2), RU2285265 (C2), NO337637 (B1), JP4404547 (B2), CA2425775 (C), EP2275819
Owner: Mycartis NV
1999 – S.C.. De Smedt and J. Demeester, C. Roeland and R. Pauwels
Priority: 16/04/1999
Assigned in designated countries:
EP1173760 (B1), AU771517 (B2), CA2370315 (C), CN1271410 (C), US8967483 (B2) , ZA200108305 (B), RU2242746 (C2), JP4500455 (B2)
Owner: Mycartis NV
- Pharm. Gaëlle Houthaeve
- 2016-2021
- W. De Vos (promotor), K. Braeckmans (promotor)
- Pharm. Dawei Hua
- 2016-2021
- S. De Smedt (promotor), C. Huang (promotor), F. Sauvage, R. Xiong
- Pharm. Joke Deprez
- 2016-2021
- S. De Smedt (promotor) , P. Jacques (promotor), I. Lentacker (promotor)
- Pharm. Thys Van de Vyver
- 2016-2021
- K. Raemdonck (promotor), S. De Smedt (promotor)
- Pharm. Laurens Raes
- 2016-2021
- K. Braeckmans (promotor)
- Pharm. Jelter Van Hoeck
- 2016-2021
- K. Raemdonck (promotor)
- Sc. Aranit Harizaj
- 2016-2020
- K. Braeckmans (promotor) , I. Lentacker (promotor) and D. Poelman (promotor)
- Pharm. Roberta Guagliardo
- 2016-2020
- K.. Raemdonck (promotor), S. De Smedt (promotor)
- Pharm. Heyang Zhang
- 2016-2020
- K. Remaut (promotor), S. De Smedt (promotor)
- Pharm. Jing Liu
- 2016-2020
- K. Braeckmans (promotor), R. Xiong (promotor)
- Pharm. PJ. Merckx
- 2015-2020
- K. Raemdonck (promotor), S. De Smedt (promotor)
- Pharm. M. Shariati
- 2015-2020
- S. De Smedt (promotor), K. Remaut (promotor), W. Ceelen (promotor)
- Pharm. S. Roovers
- 2015-2019
- S. De Smedt (promotor), S. Lentacker (promotor)
- Pharm. E. Teirlinck
- 2014-2019
- K. Braeckmans (promotor), T. Coeneye (promotor)
- Pharm. J. Devoldere
- 2014-2019
- K. Remaut (promotor), S. De Smedt (promotor)
- Pharm. R. Verbeke
- 2013-2019
- S. De Smedt (promotor), H. Dewitte (promotor)
- Pharm. L. Vermeulen
- 2014-2018
- K. Remaut (promotor), K. Braeckmans (promotor)
- Pharm. K. Peynshaert
- 2013-2018
- K. Remaut (promotor), S. De Smedt (promotor)
- Pharm. E. Zagato
- 2012-2018
- K. Braeckmans (promotor), K. Neyt (promotor, K. Remaut (promotor)
- Pharm. R. Sobral Santos
- 2013-2017
- N. Azevedo (promotor), K. Braeckmans (promotor), S. De Smedt (promotor)
- Pharm. F. Joris
- 2013-2017
- S. De Smedt (promotor), K. Raemdonck (promotor)
- M.S. R. Xiong
- 2011 – 2017
- K. Braeckmans (promotor), S. De Smedt (promotor), A. Skirtach (co-promotor)
- Pharm. G. Dakwar
- 2011 – 2016
- K. Remaut (promotor), S. De Smedt (promotor), W. Ceelen (co-promotor)
- Pharm. S. Stremersch
- 2011 – 2016
- S. De Smedt (promotor), K. Raemdonck (promotor), K. Braeckmans (co-promotor)
- Pharm. L. Wayteck
- 2011 – 2016
- S. De Smedt (promotor), K. Raemdonck (promotor)
- Ir. K. Rombouts
- 2012 – 2016
- K. Braeckmans (promotor), K. Remaut (promotor)
- Pharm. I. De Cock
- 2011 – 2016
- S. De Smedt (promotor), I. Lentacker (co-promotor)
- Pharm. L. De Backer
- 2010-2015
- S. De Smedt (promotor), K. Raemdonck (co-promotor)
- Biotechnologist O. Andries
- 2010-2015
- N. Sanders (promotor), S. De Smedt (co-promotor), T. Kitada (co-promotor)
- Pharm. H. Dewitte
- 2010-2015
- S. De Smedt (promotor), K. Breckpot (promotor), I. Lentacker (co-promotor)
- Pharm. K. Forier
- 2009- 2013
- K. Braeckmans (promoter), J. Demeester (co-promoter), K. Raemdonck (co-promoter)
- Ir. T. Martens
- 2010-2014
- K. Braeckmans (promotor), S. De Smedt (co-promotor), K. Remaut (co-promotor)
- Pharm. B. Geers
- 2009-2013
- S.C. De Smedt (promotor), J. Demeester (promotor), I. Lentacker (co-promotor)
- Ir. H. Deschout
- 2007- 2012
- K. Braeckmans (promoter), K. Neyts (co-promoter), J. Demeester (co-promoter).
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- Pharm. M.L. De Temmerman
- 2007-2012
- S.C. De Smedt (promotor), J. Demeester (promotor), J. Rejman (co-promotor)
- Ir. N. Symens
- 2007-2012 Universiteit Gent
- S.C. De Smedt (promotor), K. Remaut (co-promotor), J. Rejman (co-promotor)
- Pharm. G. Tavernier
- 2007-2012
- S.C. De Smedt (promotor), J. Rejman (co-promotor), J. Adjaye (co-promotor)
- Master in Science W. De Haes
- 2007-2012 Universiteit Antwerpen
- G. Van Ham (promotor), S.C. De Smedt (co-promotor)
- Ir. C. Huang
- 2007-2011
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Ir. D. Vercauteren
- 2006-2011
- S.C. De Smedt (co-promotor); K. Braeckmans (promotor)
- Pharm. B. Naeye
- 2006-2011
- S.C. De Smedt (promotor) J. Demeester (promotor), K. Raemdonck (co-promotor)
- Pharm. K. Raemdonck
- 2004-2009
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Pharm. K. Buyens
- 2004-2009
- S.C. De Smedt (promotor), N.N. Sanders (promotor)
- Pharm. I. Lentacker
- 2003-2009
- S.C. De Smedt (-promotor), N.N. Sanders (promotor), J. Demeester(copromotor)
- Pharm. F. Fayazpour
- 2003-2008
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Ir. S. S. Derveaux
- 2003- 2008
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Ir. S. De Koker
- 2003-2008 t
- S.C. De Smedt (co-promotor), N. Mertens (co-promotor) J. Grooten (promotor)
- Biotechnologist R. Vandenbroucke
- 2003-2008
- S.C. De Smedt (co-promotor), J. Demeester (promotor), N.N. Sanders (promotor)
- Ir. B. De Geest
- 2003 – 2006
- S.C. De Smedt (promotor), J. Demeester ( promotor)
- Gehonoreerd met de Andreas De Leenheer Prijs (2008) uitgereikt door de International Club of Flanders
- Biotechnologist L. Peeters
- 2003-2008
- S.C. De Smedt (promotor), N.N. Sanders (promotor), J. Demeester (co-promotor)
- Ir. T. Van Thienen
- 2002 – 2007
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Pharm. S. Van Tomme
- 2007
- S.C. De Smedt (promotor), W. Hennink (promotor)
- Pharm. K. Remaut
- 2001-2007
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Ir. B. Lucas
- 2000 – 2005
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Pharm. E. Van Rompaey
- 1998 – 2003
- S.C De Smedt (promotor), J. Demeester (promotor)
- Pharm. N. Sanders
- 1997-2001
- S.C De Smedt (promotor), J. Demeester (promotor)
- Gehonoreerd met de nationale prijs van het Belgisch Genootschap voor Farmaceutische Wetenschappen (2003) en de Leonardo Award (2002)
- Physicist K. Braeckmans
- 1999 -2004
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Gehonoreerd met de “Young Biotechnology Researchers Award” (2005)
- Pharm. B. Stubbe
- 1999 – 2004
- S.C De Smedt (promotor), J. Demeester (promotor)
- Ir. T. Meyvis
- 1995-1999
- S.C De Smedt (co-promotor), J. Demeester (promotor)
Publications in Press
- Photodisruption of the inner limiting membrane: exploring ICG loaded nanoparticles as photosensitizers Kaat De Clerck, Geraldine Accou, Félix Sauvage, Kevin Braeckmans, Stefaan C. De Smedt, Katrien Remaut, Karen Peynshaert Nanoparticles in Ocular Drug Delivery Systems 2022, accepted
- Non-viral siRNA delivery to T cells: challenges and opportunities in cancer immunotherapy Jelter Van Hoeck, Kevin Braeckmans, Stefaan C. De Smedt, Koen Raemdonck Biomaterials 2022, accepted
- Nanoparticle mediated targeting of toll-like receptors to treat colorectal cancer Ragna M.S. Haegebaert , Maxime Kempers, Wim Ceelen, Ine Lentacker, Katrien Remaut European Journal of Pharmaceutics and Biopharmaceutics 2022, accepted
- Modulating intracellular pathways to improve non-viral delivery of RNA therapeutics Advanced Drug Delivery Reviews Thys Van de Vyver, Stefaan De Smedt, Koen Raemdonck Advanced Drug Delivery Reviews 2021, accepted
- Non-invasive cell tracking methods for adoptive T cell therapies Jelter Van Hoeck, Christian Vanhove, Stefaan C. De Smedt, Koen Raemdonck Drug discovery today 2021, accepted
- Exploring high pressure nebulization of Pluronic F127 hydrogels for intraperitoneal drug delivery Helena Braet, Mohammad Rahimi-Gorji, Charlotte Debbaut, Ghader Ghorbaniasl, Thibault Van Walleghem, Senne Cornelis, Sarah Cosyns, Chris Vervaet, Wouter Willaert, Wim Ceelen, Stefaan C. De Smedt, Katrien Remaut European Journal of Pharmaceutics and Biopharmaceutics 2021, accepted
- Carbon quantum dots as a dual platform for the inhibition and light-based destruction of collagen fibers: implications for the treatment of eye floaters Alexandre Barras, Fe´lix Sauvage, Ine`s de Hoon, Kevin Braeckmans,Dawei Hua, Gae¨tan Buvat, Juan C. Fraire, Christophe Lethien, J. Sebag,Michael Harringtone Amar Abderrahmani, Rabah Boukherroub,Stefaan De Smedt and Sabine Szunerits Nanoscale Horizons 2021,accepted
- Surfactant Protein B Promotes Cytosolic SiRNA Delivery by Adopting a Virus-Like Mechanism of Action Guagliardo, Roberta; Herman, Lore; Penders, Jelle; Zamborlin, Agata; De Keersmaecker, Herlinde; Van de Vyver, Thijs; Verstraeten, Sandrine; Merckx, Pieterjan; Mingeot-Leclercq, Marie-Paule; Echaide, Mercedes; Perez-Gil, Jesus; Stevens, Molly; De Smedt, Stefaan; Raemdonck, Koen ACS Nano 2021, accepted